The collection originated largely from the 'Accademia di Disegno' founded in 1788.
Many works were transferred here after the suppression of religious orders in the 18th and 19th centuries.
The gallery houses rare 'biccherna' panels, which were historically used as decorative covers for the city's financial records.
The Palazzo Buonsignori dates back to the 15th century and features a late-Gothic facade.
The museum holds the 'Madonna di Crevole', an early work by Duccio di Buoninsegna.
The Pinacoteca Nazionale di Siena is located within the historic Palazzo Brigidi and Palazzo Buonsignori, housing the most comprehensive collection of Sienese painting from the 12th to the 17th century. The museum is renowned for its extensive series of 'tavole dipinte' (painted wood panels) featuring gold backgrounds from the Sienese School. Visitors can examine the stylistic evolution of masters such as Duccio di Buoninsegna, Simone Martini, and the Lorenzetti brothers. The collection is arranged chronologically across three floors, highlighting the transition from Byzantine influence to the Renaissance. A significant portion of the gallery is dedicated to the Spedale di Santa Maria della Scala collection. The building itself reflects 14th and 15th-century Sienese civil architecture with distinct gothic features. It serves as the primary repository for artworks salvaged from deconsecrated local churches. As of July 2026, the gallery continues to operate as a state-run museum under the Italian Ministry of Culture.
The internal courtyard of the Palazzo Buonsignori, which offers a quiet architectural perspective of the Sienese brickwork.
Focus on the second floor first, as it houses the most famous medieval masterpieces.
Check the official website for temporary exhibitions, as these often occupy the ground floor galleries.
Use the provided information panels to understand the transition from the Byzantine 'maniera greca' style.
Trying to see the entire collection in under an hour; the detail in the Sienese gold-ground panels requires time to appreciate.
Typically closed on Monday mornings; often follows reduced hours on Sunday afternoons.
Maintain a quiet volume, do not use flash photography, and avoid touching the frames or surfaces of the paintings.